Xylitol

Name of Product: Xylitol

Chemical Name: 1,2,3,4,5-Pentahydoxypentane
Molecular-Formula: C5H12O5
Molecular Weight: 152.15
Cas No.: [87-99-0]

Characteristics

Appearance: White crystalline or crystalline powder, it has a sweet taste odorless and a cooling.
Sensation: it water solution and transparent 1gdissolves in about 0.65ml of water. It is tiny to dissolve in the ether with Methyl alcohol, Melting Point: 92-96?, Boiling Point: 216?, 10% solution: PH5.0-7.0

Xylitol occurs naturally in many fruits and vegetables and is even produced by the human body during normal metabolism, produced commercially from plants such as corncob, birch and fibrous vegetation, xylitol has the same sweetness and bulk as sucrose with one-third calories (about 2.4 calories per Gram) and no unpleased aftertaste, It quickly dissolve and produces a cooling sensation in the mouth.

(1) Xylitol drug line---A Diabetic Fighter, Nutritional Agent and the Best Sweetener

Diabetes is known as the top third killer behind AIDS and cancer. It is therefore named "Sub-cancer" According to a survey conducted by the Chinese Academy of Preventive Medical Science, of over 40,000 permanent residents aged 20 to 74 across 11 provinces/municipalities, the morbidity ratio of diabetes was 3.21% and 4.76% has lower tolerance to sugar. That translates into 5000 to 6000 persons with either diabetic or lower tolerance to sugar. Out of which, 5% belongs to the former with most of the sufferers coming from children and young people and patients suffering acute attack and severe deficiency of insulin. The rest 95% belongs to the later with most of the sufferers from old people and patients of chronic symptoms and likely to be overlooked. Mere diabetes is not a serious problem. But its syndromes may be dangerous. For example, the acute syndromes may include ketonemia oxidosis, high permeability coma and lactic acidosis. The chronic
syndromes may cover cardiovascular, retina, renal and nervous pathologic process. Such syndromes not only afflict the patients but also endanger patient's life.

Character

Xylitol, namely pentose alcohol, is white crystal or crystal powder without odor. It tastes cool with the same saccharinity as that in cane sugar and the same calorific power as in glucose.
A cure applied in medical and health services
1. As a cure for diabetics, Xylitol serves as an intermediate of sugar metabolism. By its unique way of metabolism, it produces 6-phosphofructose and phosphoglyceraldehyde directly via metabolism of pentose phosphate pathway without the necessity of promotion by insulin (it even promotes secretion of insulin). The 6-phosphofructose and phosphoglyceraldehyde thus produced can supply energy to the cells, maintain metabolic balance in body and effectively control diabetic syndromes. After use of this product, the commonly seen diabetic symptoms will be relieved gradually, and the users will be reported of reduced glycosuria. Through persistent use of this product, the symptoms will disappear.
2. As a cure for improving hepatic function, Xylitol can slow down the producing process of fatty acid in plasma, but won’t cause higher blood sugar. After intake, the level of lactic acid, Pyruvic acid and glucose in the blood will decrease, and insulin level will go up slightly. At the same time, the hepatic starch will increase while the aminotransferase will decrease. This is good for hepatitis B persisting type and cirrhosis. Obviously, it is an effective drug for hepatitis sufferers, especially for diabetics with accompanying hepatitis syndrome.
3. Bearing the effect of anti-ketone body, this product is an ideal anti-ketone drug for diabetics and starvation ketonemia.

Other medical effects of Xylitol

1. It may be used as an infusion in surgical operation. It's clinically proved that Xylitol has better blood stability than glucose, being an ideal sugar supplement used in internal and surgical treatment, especially after surgical anesthesia and surgical operation when there is something wrong with glucose metabolism and glucose can' t be utilized. Xylitol promotes the flow of red blood cells (RBC), maintains the negative charge of RBC, and controls the content of blood glutathione, thus shortening the healing process of surgical location.
2. It is effective in controlling formation of glycerol, neutral fat and free fatty acid, thus may be used to control weight gain and cure obesity.
3. Xylitol has good heat stability. It will not generate chemical reaction when heated together with amino acid. Therefore, it may be mixed with amino acids and applied to various agents. Xylitol is also good for gastric secretion, pancreatic & biliary activity, adrenal cortex hormone, NADPH and ATP, suitable for aged and weak people.
4. As Xylitol is absorbed by the intestinal wall at a pace slower than other sugars, it may be used in combination with laxative for senile constipation, and won’t cause pain and side effect.

Directions for use

To be infused in water before use, or to be taken with meal. For adults, 2 to 3 times daily with dosage of 20 to 40 g. For children, half of the dosage or follow doctor’s advice.
Cautions
1. In case of minor diarrhea with first time user or user taking this product at excessive dosage, reduce the dosage and the diarrhea will disappear. There is no other side effect.
2. Xylitol is likely to absorb moisture. Do not expose it to moisture when it’s stored

(2) Xylitol anticarious product line

The anticarious mechanism

Xylitol is resistant to the S mutant in mouth and won’t be fermented into harmful dental plaque acid. It inhibits the growth of dental plaque and acidic formation, stimulates the flow of protective saliva, changes the constituents of saliva, slows the reducing process of the pH value, and reduces the dental decay due to the plaque acid. Cane sugar also promotes saliva secretion, but that’s not enough to overweigh the acidic effect caused by the streptococcal mutant. By contrast, after Xylitol is taken, the basic amino acid and ammonia concentration in the saliva and at the carious plaque will rise, pushing up the pH value. As a result, the xylitol-5-phosphate will resettle on the enamel, thus re-strengthening the teeth and repairing impaired enamel. Xylitol can inhibit bacterial reproduction and acid formation, thus leading to 90% reduction of acidic product by lactic acid bacteria and streptococcal mutant and resulting decrease of bacteria-dependent fatty phosphoric acid in the saliva and the plaques. As a result, the bacteria adsorbed to the dental surface are inhibited, and plaques are reduced in number.